Effects of Procyclidine on Eye Movements in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Eye Movements and Schizophrenia
Smooth pursuit eye movements (SPEM) has been reported to be abnormal in schizophrenic patients. 30 schizophrenic patients and 15 normal subjects were examined for the quality of their smooth pursuit performance. 73.33% of the schizophrenics and 40% of the normal subjects had 'impaired' pursuit performance. The significance of the findings has been discussed.
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Previous studies have shown that smooth pursuit eye movements are impaired in patients with schizophrenia. However, under normal viewing conditions, targets move not only in the frontoparallel plane but also in depth, and tracking them requires both smooth pursuit and vergence eye movements. Although previous studies in humans and non-human primates suggest that these two eye movement subsystem...
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The antisaccade task can be used to test the voluntary control of saccadic eye movements (SEMs). In many disorders with postulated hyperdopaminergic neurotransmission, there are reports of abnormalities in SEMs. To further investigate this, the role of dopamine in SEMs, performance on an antisaccade task was examined in subjects with a history of amphetamine use (a dopamine releaser and reuptak...
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OBJECTIVE Valproic acid (VPA) has been suggested as a potential adjunct therapy in schizophrenia for the treatment of clinical symptoms and cognitive deficits. Here, we investigate the effects of VPA on clinical symptoms and saccadic eye movements while controlling for multiple medication effects. METHODS Remitted and first-episode schizophrenia patients taking haloperidol were given adjunct ...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2003
ISSN: 0893-133X,1740-634X
DOI: 10.1038/sj.npp.1300286